小鸡快跑
随着鸡基因组草图的完成，更多的生物学家将目光投向了鸡。作为第一个完成测序的鸟类，这被认为在哺乳动物和其它物种(果蝇，鱼类等)之间架起了桥梁。鸡有超过200个基因和已知的味觉受体基因很相似，具此人们推断鸡也有味觉。
到底是什么使得生物学家对鸡如此感兴趣？显然不只是香喷喷的油炸鸡大腿。
第一，对于经典的遗传学研究，鸡宜于饲养和管理，繁殖快，产仔多且有易于分辨的特征。
第二，鸡有为数众多的天然突变体。在过去的60年里，人们已经饲养了具有不同遗传学特征的不同品种的鸡，研究者可以进一步分析遗传学的突变情况。
第三，是研究脊椎动物的极好的模型。鸡胚胎发育在形态学上和哺乳动物相似，可以用鸡蛋来研究(又是鸡蛋)。事实上我们对于四肢形成的知识即是从对鸡的研究中所得。
第四，是人类疾病的理想模型。鸡很多疾病的症状和病人相似，包括肌无力，突发性意识丧失以及免疫低下。对鸡的研究有助于阐明遗传的起因。
第五，可以用于病毒感染的研究。目前在人身上已经发现禽流感病毒以及其它动物源性病毒，鸡和哺乳动物有相似的免疫反应，有助于研究感染的机制以及遗传易感性的机制。
最后，以前人们普遍认为外科医生最幸福，因为他们可以给狗和猪做手术；搞生理的可以拿兔子做实验，兔子肉也不赖；搞免疫的总是和小鼠打交道，虽说肉很嫩，总有些心理不适；至于鸡给我们带来了极大的希望，浑身都是宝啊，公鸡打鸣，连闹钟也省了，母鸡还下蛋。
世上没有救世主。小鸡，快跑。
昨天MY回家问我，既然把鸡已经搞清楚了，建议养鸡场把促进鸡翅膀发育和鸡大腿发育的基因分别注入，分开车间来饲养。这样就可以在肯德鸡吃到大大的翅膀和大腿了。
每天看到我那些敲除基因的老鼠痛不欲生的活着，我真的不知道我们做的是好事还是坏事。曾经很长一段时间老鼠都在我的梦境里向我所要性命，听了前辈的建议，参加了一次给动物举行的葬礼才算平息下来。
Comment by blooming — December 22, 2004 @ 12:36 am
有一种比利时牛，肌肉特别发达。好像是和Follistatin相关的基因，八楼在做这方面的课题。目前已经有开发的生物试剂，人人都可以成为施瓦辛格。不过转基因的食物是很危险滴。
Comment by hanhongwei — December 22, 2004 @ 1:22 am
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